bioRxiv
Blocking an RNA counters aging-related gene activity in cells
Cell experiments found that inhibiting the RNA lowered DNA-based age estimates but made DNA markings less consistent with cell identity.Cell experiments found that inhibiting the RNA lowered DNA-based age estimates but made DNA markings less consistent with cell identity.
Preprint: animal cell studyMechanisms
Who was studiedSomatic cells
What changedBlocking miR-29 shifted gene activity away from aging-associated patterns
The catchGene activity and DNA-based age estimates are stand-ins for cellular rejuvenation