Nature Cardiovascular Research
Blood-cell gene loss impairs heart recovery in mice
In mouse experiments, blocking an immune signal counteracted the harmful heart effects of losing KDM6A in blood-forming cells.In mouse experiments, blocking an immune signal counteracted the harmful heart effects of losing KDM6A in blood-forming cells.
Mouse studyMechanisms
Who was studiedMice with hematopoietic KDM6A deletion, through day 28
What changedHeart pumping function was lower at day 28 after a heart attack in mice lacking blood-cell KDM6A than in control mice
The catchHeart function follow-up stopped at day 28; later recovery was not measured