HX1 lipid nanoparticles

HX1 lipid nanoparticles has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 3, 2026: “Tiny fat-based particles delivered RNA to mouse brains”.

Intervention

1 paper studies it2 findingsUpdated

1 new paper in 30 daysSee all 1

None of its findings points the other way.

  • 1 lab
  • Animals1

What did studies of HX1 lipid nanoparticles find?

2

Studies of HX1 lipid nanoparticles measured 2 outcomes; the most studied are luciferase mRNA delivery to the brain (1 study) and brain gene editing (1).

Luciferase mRNA delivery to the brain

upin non-human primate1

1 study
  1. HX1 lipid nanoparticles induce luciferase mRNA delivery to the brain in non-human primate.

    “effectively delivered luciferase mRNA to the brain of a non-human primate.”

    Animalscarrying luciferase mRNAbrain

    Tiny fat-based particles delivered RNA to mouse brains

    Nature nanotechnology

Brain gene editing

upin mice1

1 study
  1. HX1 lipid nanoparticles induce brain gene editing in mice.

    “HX1 LNPs also enabled efficient gene editing in mouse brains via co-delivery of CRISPR mRNA and guide RNA”

    Animalsco-delivery of CRISPR mRNA and guide RNAbrain

    Tiny fat-based particles delivered RNA to mouse brains

    Nature nanotechnology

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
Nature Nanotechnology

Tiny fat-based particles delivered RNA to mouse brains

In mouse experiments, the particles delivered gene-editing components to the brain and carried RNA that reduced radiation-induced brain injury.In mouse experiments, the particles delivered gene-editing components to the brain and carried RNA that reduced radiation-induced brain injury.

Mouse studyInterventions