Human adipose tissue-derived stem cell exosomes

1. Human adipose tissue-derived stem cell exosomes improve Physician's Global Aesthetic Improvement Scale in humans.

   “Both the PGAIS and patient satisfaction scores were significantly higher on the experimental side.”

   Human trialskin8 weeksn = 16

   Adipose tissue-derived stem cell exosomes enhance skin barrier function and show exploratory associations with the skin mycobiome in aging skin

   Journal of microbiology (Seoul, Korea)·Jun 30, 2026

More on Physician's Global Aesthetic Improvement Scale

1. Human adipose tissue-derived stem cell exosomes increase skin elasticity in humans.

   “significant increase in elasticity (R2/R5/R7 values, p < 0.001).”

   Human trialskin8 weeksn = 16

   Adipose tissue-derived stem cell exosomes enhance skin barrier function and show exploratory associations with the skin mycobiome in aging skin

   Journal of microbiology (Seoul, Korea)·Jun 30, 2026

More on Skin elasticity

1. Human adipose tissue-derived stem cell exosomes increase stratum corneum hydration in humans.

   “increased hydration (p < 0.001 at all time points) with a significant increase in elasticity (R2/R5/R7 values, p < 0.001).”

   Human trialskin8 weeksn = 16

   Adipose tissue-derived stem cell exosomes enhance skin barrier function and show exploratory associations with the skin mycobiome in aging skin

   Journal of microbiology (Seoul, Korea)·Jun 30, 2026

More on Stratum corneum hydration

1. Human adipose tissue-derived stem cell exosomes decrease transepidermal water loss in humans.

   “HACS treatment significantly reduced TEWL (p = 0.006 at week 2; p = 0.009 at week 8)”

   Human trialskin8 weeksn = 16

   Adipose tissue-derived stem cell exosomes enhance skin barrier function and show exploratory associations with the skin mycobiome in aging skin

   Journal of microbiology (Seoul, Korea)·Jun 30, 2026

More on Transepidermal water loss