AgingResearch.NewsJoin free

Homehealth

Intervention

1 paper6 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Age UK and 1 more
  • Human trial1

Outcomes

6

Incremental costs

downin humans1

1 study

  1. Homehealth decreases incremental costs in humans (-796 (95% CI -2016 to 424)).

    “HomeHealth dominates treatment as usual with a negative point estimate for incremental costs (-796, 95% confidence interval -2016 to 424)”

    Human trialMild frailty; compared with treatment as usual

    Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial

    Health technology assessment (Winchester, England)9 Sep 2025

Unplanned hospital admissions

downin humans1

1 study

  1. Homehealth decreases unplanned hospital admissions in humans (35% reduction; incidence rate ratio 0.65 (95% CI 0.54 to 0.92)).

    “reduced unplanned admissions (incidence rate ratio 0.65, 95% confidence interval 0.54 to 0.92)”

    Human trialMild frailty; compared with treatment as usual12 months

    Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial

    Health technology assessment (Winchester, England)9 Sep 2025

Well-being

upin humans1

1 study

  1. Homehealth improves well-being in humans (1.449 (95% CI 0.124 to 2.775)).

    “At 12 months, we found significant improvements in well-being (1.449, 95% confidence interval 0.124 to 2.775)”

    Human trialMild frailty; compared with treatment as usual12 months

    Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial

    Health technology assessment (Winchester, England)9 Sep 2025

Frailty phenotype score

downin humans1

1 study

  1. Homehealth decreases frailty phenotype score in humans (-0.252 (95% CI -0.487 to -0.017)).

    “and frailty phenotype score (-0.252, 95% confidence interval -0.487 to -0.017).”

    Human trialMild frailty; compared with treatment as usual6 months

    Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial

    Health technology assessment (Winchester, England)9 Sep 2025

Psychological distress

downin humans1

1 study

  1. Homehealth decreases psychological distress in humans (-1.237 (95% CI -2.127 to -0.348)).

    “At 6 months, we found small significant reductions in psychological distress (-1.237, 95% confidence interval -2.127 to -0.348)”

    Human trialMild frailty; compared with treatment as usual6 months

    Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial

    Health technology assessment (Winchester, England)9 Sep 2025

Independence in activities of daily living

no changein humans1

1 study

  1. Homehealth has no effect on independence in activities of daily living in humans (Modified Barthel Index difference 0.250 (95% CI -0.932 to 1.432)).

    “HomeHealth did not improve Barthel Index scores at 12 months (0.250, 95% confidence interval -0.932 to 1.432).”

    Human trialCommunity-dwelling older people with mild frailty; compared with treatment as usual12 months64% femalesn = 388

    Enabling health and maintaining independence for older people at home: the 'HomeHealth' Randomised Controlled Trial

    Health technology assessment (Winchester, England)9 Sep 2025

Latest

Related