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HIV-1 viral proteins

Exposure

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Institute of Child Health and Human Development and 5 more
  • Animals1

Outcomes

2

Long-term episodic memory

downin rats1

1 study

  1. HIV-1 viral proteins impair long-term episodic memory in rats.

    “Locomotor activity revealed deficits in intrasession habituation, suggestive of a disruption in long-term episodic memory, in HIV-1 Tg animals.”

    AnimalsHIV-1 transgenic

    Evolution of the HIV-1 transgenic rat: utility in assessing the progression of HIV-1-associated neurocognitive disorders

    Journal of neurovirologyJul 20, 2017

Temporal processing

downin rats1

1 study

  1. HIV-1 viral proteins impair temporal processing in rats.

    “Cross-modal PPI revealed significant alterations in the development of temporal processing in HIV-1 Tg animals relative to controls”

    AnimalsHIV-1 transgenic

    Evolution of the HIV-1 transgenic rat: utility in assessing the progression of HIV-1-associated neurocognitive disorders

    Journal of neurovirologyJul 20, 2017

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