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High-intensity interval training + vitamin D

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Deanship of Scientific Research, King Saud University and 1 more
  • Human trial1

Outcomes

2

Osteocalcin

upin humans1

1 study

  1. High-intensity interval training + vitamin D increases osteocalcin in humans.

    “Serum samples revealed that bone resorption markers, osteocalcin, total calcium, s-BAP, and vitamin 25(OH) D significantly improved in all groups; there was greater improvement in the HIIT training-vitamin D group”

    Human trialosteoporosis16 weeksfemalesn = 120

    Concurrent effects of high-intensity interval training and vitamin D supplementation on bone metabolism among women diagnosed with osteoporosis: a randomized controlled trial

    BMC musculoskeletal disorders21 Apr 2025

More on Osteocalcin

Bone mineral density

upin humans1

1 study

  1. High-intensity interval training + vitamin D increases bone mineral density in humans.

    “Furthermore, the HIIT training-vitamin D group showed improvements in hip (right and left) and lumbar spine BMD than the HIIT training, Vitamin D, and Control groups.”

    Human trialosteoporosisbone16 weeksfemalesn = 120

    Concurrent effects of high-intensity interval training and vitamin D supplementation on bone metabolism among women diagnosed with osteoporosis: a randomized controlled trial

    BMC musculoskeletal disorders21 Apr 2025

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