Henagliflozin
Intervention1 paper3 findingsPubChem 56832738
- Human trial1
Outcomes
3NT-proBNP
no changein humans1Moderate certainty
1 study
NT-proBNP
no changein humans1Moderate certainty
Henagliflozin has no effect on NT-proBNP in humans.
Human trialin dialysis patients with HFpEF24 weeksn = 112
Effects and Safety of Henagliflozin on Cardiac Structure in Dialysis Patients with Heart Failure with Preserved Ejection Fraction · Clinical journal of the American Society of Nephrology : CJASN · 2 Sep 2026
Left atrial volume index
no changein humans1Moderate certainty
1 study
Left atrial volume index
no changein humans1Moderate certainty
Henagliflozin has no effect on left atrial volume index in humans.
Human trialin dialysis patients with HFpEFheart24 weeksn = 112
Effects and Safety of Henagliflozin on Cardiac Structure in Dialysis Patients with Heart Failure with Preserved Ejection Fraction · Clinical journal of the American Society of Nephrology : CJASN · 2 Sep 2026
Left ventricular mass index
downin humans1Moderate certainty
1 study
Left ventricular mass index
downin humans1Moderate certainty
Henagliflozin decreases left ventricular mass index in humans (-5.27 g/m2 (95% CI, -10.02 to -0.53 g/m2)).
Human trialin dialysis patients with HFpEFheart24 weeksn = 112
Effects and Safety of Henagliflozin on Cardiac Structure in Dialysis Patients with Heart Failure with Preserved Ejection Fraction · Clinical journal of the American Society of Nephrology : CJASN · 2 Sep 2026