Glutamate carboxypeptidase II inhibitor

Glutamate carboxypeptidase II inhibitor has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 2, 2026: “Brain enzyme contributes to memory problems after surgery in mice”.

Intervention

1 paper studies it1 findingUpdated

See all 1 papers on glutamate carboxypeptidase II inhibitor

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

Mice: a single group. Cells, worms or flies and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: Cell Science Research Foundation and others
  • Animals1

What did studies of glutamate carboxypeptidase II inhibitor find?

1

Studies of glutamate carboxypeptidase II inhibitor measured 1 outcome; the most studied are cognitive function (1 study).

Cognitive function

upin mice1

1 study
  1. Glutamate carboxypeptidase II inhibitor improves cognitive function in mice (pharmacological GCPII inhibition).

    “consistent with pharmacological GCPII inhibition ameliorating glutamate levels, AQP4 polarization, and cognitive performance”

    Animalspharmacological GCPII inhibition

    Brain enzyme contributes to memory problems after surgery in mice

    Alzheimer's & dementia : the journal of the Alzheimer's Association

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months
Alzheimer's & Dementia

Brain enzyme contributes to memory problems after surgery in mice

Experiments in mice aged 18–20 months implicated an enzyme in brain support cells in male-specific memory problems during the week after surgery.Experiments in mice aged 18–20 months implicated an enzyme in brain support cells in male-specific memory problems during the week after surgery.

Mouse studyMechanisms