Glucocorticoid receptor inhibitor

Glucocorticoid receptor inhibitor improves aging phenotypes in killifish.

“pharmacological inhibition of glucocorticoid receptor activity starting at middle-age led to significant rescue of key molecular and cellular aging phenotypes”

Animalsbrain

A multi-omic atlas in the African turquoise killifish reveals increased glucocorticoid signaling as a hallmark of brain aging

bioRxiv : the preprint server for biology·10 Apr 2026Preprint