GIFT-7 tumor vaccine

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funder: National Institute of Neurological Disorders and Stroke
  • Animals1

Outcomes

3

Immune response

upin mice1

1 study
  1. GIFT-7 tumor vaccine increases immune response in mice.

    “GIFT-7 vaccination resulted in increased T-cell trafficking to the brain and robust Th-17 long-term effector memory T-cell formation”

    Animalsin aged syngeneic mouse models of glioblastoma

    GM-CSF and IL-7 fusion cytokine engineered tumor vaccine generates long-term Th-17 memory cells and increases overall survival in aged syngeneic mouse models of glioblastoma

    Aging cellMay 11, 2023

More on Immune response

Thymus

upin mice1

1 study
  1. GIFT-7 tumor vaccine improves thymus in mice.

    “peripheral vaccination with GIFT-7TVax resulted in thymic regeneration”

    Animalsin aged syngeneic mouse models of glioblastoma

    GM-CSF and IL-7 fusion cytokine engineered tumor vaccine generates long-term Th-17 memory cells and increases overall survival in aged syngeneic mouse models of glioblastoma

    Aging cellMay 11, 2023

Lifespan

upin mice1

1 study
  1. GIFT-7 tumor vaccine increases lifespan in mice.

    “increases overall survival in aged syngeneic mouse models of glioblastoma”

    Animalsin aged syngeneic mouse models of glioblastoma

    GM-CSF and IL-7 fusion cytokine engineered tumor vaccine generates long-term Th-17 memory cells and increases overall survival in aged syngeneic mouse models of glioblastoma

    Aging cellMay 11, 2023

Latest