Germline depletion

Germline depletion has been studied in 1 paper since 2024: none in people yet, 1 in animals. The research so far is in animals. The newest paper, May 15, 2024: “The killifish germline regulates longevity and somatic repair in a sex-specific manner”.

Intervention

1 paper studies it2 findingsUpdated

See all 1

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: Abisch-Frenkel-Stiftung and 7 more
  • Animals1

What did studies of Germline depletion find?

2

Studies of Germline depletion measured 2 outcomes; the most studied are metabolic functions (1 study) and lifespan (1).

Metabolic functions

upin killifish1

1 study
  1. Germline depletion improves metabolic functions in killifish.

    “germline-depleted males instead showed an extension in lifespan and rejuvenated metabolic functions”

    Animalsmales

    The killifish germline regulates longevity and somatic repair in a sex-specific manner

    Nature aging

Lifespan

upin killifish1

1 study
  1. Germline depletion extends lifespan in killifish.

    “germline-depleted males instead showed an extension in lifespan”

    Animalsmales

    The killifish germline regulates longevity and somatic repair in a sex-specific manner

    Nature aging

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