Kidney International Reports
Opioids linked to higher death risk in chronic kidney disease
Estimated death risk over 28 days was 0.4% after one 90-day opioid prescription period versus 0.6% after six in adults with chronic kidney disease.Estimated death risk over 28 days was 0.4% after one 90-day opioid prescription period versus 0.6% after six in adults with chronic kidney disease.
Cohort · 21,440 peopleChronic kidney disease
Who was studied21,440 adults with chronic kidney disease, median 4.3 years
What changedDeath was more likely with 6 continuous 90-day opioid stretches than none (odds ratio 1.68)
The catchWorsening frailty and multimorbidity can drive both opioid prescribing and death
