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Exercise + fisetin

Intervention

5 findings

At a glance

The findings reach people, from one lab or study. 1 lab in 2 countries.

“The TF group exhibited the most substantial and statistically significant decline in asprosin levels compared to the P group (mean difference = −0.567 ng/mL; p < 0.001; 95% CI [−0.728, −0.406]).”
The Effects of Interval Resistance-Aerobic Training and Fisetin Supplementation on Asprosin and Selected Adipokines in Obese Men: A Double-Blind Randomized Control TrialNutrients2026doi:10.3390/nu18030433
Humans: a single group. Cells, worms or flies and mice: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 2 countries
  • Funder: Hakim Sabzevari University

What did studies of exercise + fisetin find?

5

Studies of exercise + fisetin measured 5 outcomes, among them LDL-C, body weight and adiponectin.

LDL-C

downin humans1

1 study

  1. Exercise + fisetin decreases LDL-C in humans (-18.745 mg/dL).

    “The TF group exhibited a greater reduction compared to other groups and statistically significant decrease in LDL-C levels compared to the P group (mean difference = −18.745 mg/dL; p < 0.001; 95% CI [−21.326, −16.164]).”

    Human trial12 weeksmalesn = 60

    The Effects of Interval Resistance-Aerobic Training and Fisetin Supplementation on Asprosin and Selected Adipokines in Obese Men: A Double-Blind Randomized Control Trial

    Nutrients

More on LDL-C

Body weight

downin humans1

1 study

  1. Exercise + fisetin decreases body weight in humans (-4.004 kg).

    “Specifically, the TF group demonstrated a significant reduction in body weight compared to the P group (mean difference = −4.004 kg; p < 0.001; 95% CI −6.439, −1.569]).”

    Human trial12 weeksmalesn = 60

    The Effects of Interval Resistance-Aerobic Training and Fisetin Supplementation on Asprosin and Selected Adipokines in Obese Men: A Double-Blind Randomized Control Trial

    Nutrients

Adiponectin

upin humans1

1 study

  1. Exercise + fisetin increases adiponectin in humans (4.385 ng/mL).

    “Bonferroni-corrected pairwise comparisons further elucidated the efficacy of the protocols; specifically, the TF group demonstrated a significant increase in adiponectin levels compared to the P (mean difference = 4.385 ng/mL; p < 0.001; 95% CI [2.078, 6.691]).”

    Human trial12 weeksmalesn = 60

    The Effects of Interval Resistance-Aerobic Training and Fisetin Supplementation on Asprosin and Selected Adipokines in Obese Men: A Double-Blind Randomized Control Trial

    Nutrients

More on Adiponectin

MCP-1

downin humans1

1 study

  1. Exercise + fisetin decreases MCP-1 in humans (-83.053 pg/mL).

    “The TF group exhibited the most substantial decrease in MCP-1 levels relative to the P group (mean difference = −83.053 pg/mL; p < 0.001; 95% CI [−108.691, −57.415]).”

    Human trial12 weeksmalesn = 60

    The Effects of Interval Resistance-Aerobic Training and Fisetin Supplementation on Asprosin and Selected Adipokines in Obese Men: A Double-Blind Randomized Control Trial

    Nutrients

More on MCP-1

Asprosin

downin humans1

1 study

  1. Exercise + fisetin decreases asprosin in humans (-0.567 ng/mL).

    “The TF group exhibited the most substantial and statistically significant decline in asprosin levels compared to the P group (mean difference = −0.567 ng/mL; p < 0.001; 95% CI [−0.728, −0.406]).”

    Human trial12 weeksmalesn = 60

    The Effects of Interval Resistance-Aerobic Training and Fisetin Supplementation on Asprosin and Selected Adipokines in Obese Men: A Double-Blind Randomized Control Trial

    Nutrients

More on Asprosin