DPP4-CAR-NK cells

1 paper4 findings

One mouse study reports that DPP4-CAR-NK cells improve metabolic homeostasis and liver function while reducing liver fibrosis and liver cellular senescence in CCl4-induced liver fibrosis and natural ageing.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: National Natural Science Foundation of China and 1 more

Animals1

Outcomes

Cellular senescence

downin mice1

1 study

DPP4-CAR-NK cells decrease cellular senescence in mice.
Animalsin CCl4-induced liver fibrotic and naturally aged miceliver
Targeting senescent cells with dipeptidyl peptidase 4-CAR-NK cells alleviates liver fibrosis and reverses metabolic dysfunction
Acta pharmaceutica Sinica. B1 Jul 2026

Latest

1 in 12 months

Acta Pharmaceutica Sinica B21 Sep

Targeting senescent cells with dipeptidyl peptidase 4-CAR-NK cells alleviates liver fibrosis and reverses metabolic dysfunction

Experiments in miceLiver fibrosis

Paper

DPP4-CAR-NK cells

Outcomes

Latest

Targeting senescent cells with dipeptidyl peptidase 4-CAR-NK cells alleviates liver fibrosis and reverses metabolic dysfunction

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