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Disability benefits

Exposure

1 paper5 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Institute of Arthritis and Musculoskeletal and Skin Diseases and 1 more
  • Humans1

Associations

5

GrimAge epigenetic age acceleration

upin humans1

1 study

  1. Disability benefits are associated with GrimAge epigenetic age acceleration in humans.

    “participants receiving disability benefits had GrimAge epigenetic age acceleration, while employed participants had epigenetic age deceleration (t21 = -2.256, p = .017).”

    HumansNonspecific chronic low back pain; receiving disability benefits versus employed

    An Exploratory Study of the Biological, Psychological, and Social Impact of Employment Versus Disability in Chronic Low Back Pain

    Western journal of nursing research27 Jul 2025

More on GrimAge epigenetic age acceleration

Pain resilience

downin humans1

1 study

  1. Disability benefits are associated with pain resilience in humans.

    “but lower pain resilience (t23 = 3.422, p = .001) than participants who were employed.”

    HumansNonspecific chronic low back pain; receiving disability benefits versus employed

    An Exploratory Study of the Biological, Psychological, and Social Impact of Employment Versus Disability in Chronic Low Back Pain

    Western journal of nursing research27 Jul 2025

Pain interference

upin humans1

1 study

  1. Disability benefits are associated with pain interference in humans.

    “pain interference (t23 = -5.288, p < .001)”

    HumansNonspecific chronic low back pain; receiving disability benefits versus employed

    An Exploratory Study of the Biological, Psychological, and Social Impact of Employment Versus Disability in Chronic Low Back Pain

    Western journal of nursing research27 Jul 2025

Pain intensity

upin humans1

1 study

  1. Disability benefits are associated with pain intensity in humans.

    “pain intensity (t23 = -4.195, p < .001)”

    HumansNonspecific chronic low back pain; receiving disability benefits versus employed

    An Exploratory Study of the Biological, Psychological, and Social Impact of Employment Versus Disability in Chronic Low Back Pain

    Western journal of nursing research27 Jul 2025

Depressive symptoms

upin humans1

1 study

  1. Disability benefits are associated with depressive symptoms in humans.

    “depressive symptoms (t23 = -4.195, p < .001)”

    HumansNonspecific chronic low back pain; receiving disability benefits versus employed

    An Exploratory Study of the Biological, Psychological, and Social Impact of Employment Versus Disability in Chronic Low Back Pain

    Western journal of nursing research27 Jul 2025

More on Depressive symptoms

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