Diosmin

1. Diosmin decreases XDH in rats.

   “it attenuated the age-related upregulation of Xdh.”

   Animalsaged ratsmesenteric resistance artery50 mg/kg/day3 monthsmales

   Diosmin Attenuates Age-Associated Vascular Oxidative Stress and Endothelial Dysfunction in Aged Rats

   Foods (Basel, Switzerland)·7 Aug 2026

More on XDH

1. Diosmin decreases lipopolysaccharide-binding protein in rats.

   “decreased plasma MDA and LBP levels, whereas TNF remained unchanged.”

   Animalsaged ratsplasma50 mg/kg/day3 monthsmales

   Diosmin Attenuates Age-Associated Vascular Oxidative Stress and Endothelial Dysfunction in Aged Rats

   Foods (Basel, Switzerland)·7 Aug 2026

More on Lipopolysaccharide-binding protein

1. Diosmin decreases malondialdehyde in rats.

   “These effects were accompanied by decreased plasma MDA and LBP levels”

   Animalsaged ratsplasma50 mg/kg/day3 monthsmales

   Diosmin Attenuates Age-Associated Vascular Oxidative Stress and Endothelial Dysfunction in Aged Rats

   Foods (Basel, Switzerland)·7 Aug 2026

More on Malondialdehyde

1. Diosmin decreases vascular oxidative stress in rats.

   “Diosmin also significantly reduced vascular DHE and MitoSOX fluorescence in aged animals.”

   Animalsaged ratsmesenteric resistance artery50 mg/kg/day3 monthsmales

   Diosmin Attenuates Age-Associated Vascular Oxidative Stress and Endothelial Dysfunction in Aged Rats

   Foods (Basel, Switzerland)·7 Aug 2026

1. Diosmin improves endothelial function in rats.

   “Chronic diosmin supplementation partially restored endothelial function.”

   Animalsaged ratsmesenteric resistance artery50 mg/kg/day3 monthsmales

   Diosmin Attenuates Age-Associated Vascular Oxidative Stress and Endothelial Dysfunction in Aged Rats

   Foods (Basel, Switzerland)·7 Aug 2026