Delapril + hydrochlorothiazide

Delapril + hydrochlorothiazide extends lifespan in rats (did not reach 50% mortality at 44 weeks).

“The groups treated with the highest dose of delapril and hydrochlorothiazide or with the intermediate or highest dose of delapril and indapamide did not reach 50% mortality”

Animalssalt-loaded SHRsp6 mg/kg/day delapril + 2.5 mg/kg/day hydrochlorothiazide44 weeks

Protective effects of delapril combined with indapamide or hydrochlorothiazide in spontaneously hypertensive stroke-prone rats: a comparative dose-response analysis

Journal of cardiovascular pharmacology·1 Sep 2000