Danish guideline implementation

1. Danish guideline implementation prevents cardiovascular death in silico (compared with real-world outcomes, simulated) (196 cardiovascular deaths annually).

   “implementation of the Danish guideline could annually prevent 589 strokes, 491 myocardial infarctions, 581 revascularisations and 196 cardiovascular deaths”

   In silicocompared with real-world outcomes, simulated

   Nationwide LDL-C goal attainment in high-risk and very-high-risk patients in Denmark: real-world lipid management and simulated impact of guideline implementation

   Open heart·Sep 7, 2026

1. Danish guideline implementation increases LDL-C goal attainment in silico (simulated optimal implementation) (to 91.9% primary and 63.5% secondary prevention, from 39.8% primary observed).

   “With optimal implementation, attainment increased to 91.9% (primary) and 63.5% (secondary) under the Danish guideline”

   In silicosimulated optimal implementation

   Nationwide LDL-C goal attainment in high-risk and very-high-risk patients in Denmark: real-world lipid management and simulated impact of guideline implementation

   Open heart·Sep 7, 2026

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