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Daily uplifts

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: Université du Luxembourg
  • Humans1

Outcomes

1

Positive affect

upin humans1

1 study

  1. Daily uplifts increase positive affect in humans.

    “The association between uplift occurrence and positive affect was moderated by daily age-related gains, with more positive affect being experienced on days with more uplifts and below-average age-related gains.”

    Humanson days with more uplifts and below-average age-related gains

    Emotional experience related to daily uplifts and stressors: age-differential effects in the context of age-related gains and losses

    The journals of gerontology. Series B, Psychological sciences and social sciences9 Sep 2025

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