Cryoprotective agents

Intervention2 papers4 findingsMeSH D003451

  • Cells1

Outcomes

4

Cell recovery

upin cells1Very low certainty

1 study
  1. Cryoprotective agents increase cell recovery in cells (96% vs around 10%).

    Cellsunfrozen liquid bed preservation at -25 °Cn = 18

    Unfrozen Liquid Beds Enable Soft Spheroid Preservation at -25 °C · ACS applied bio materials · 7 Sep 2026

Osmotic damage

upin reviews1

1 study
  1. Cryoprotective agents induce osmotic damage.

    Reviewexcess exposure

    Mass Transfer in Cryopreservation at Multiple Scales: Cells, Tissues, and Organs · Methods in molecular biology (Clifton, N.J.) · 1 Jan 2026

Ice formation

downin reviews1

1 study
  1. Cryoprotective agents inhibit ice formation.

    Review

    Mass Transfer in Cryopreservation at Multiple Scales: Cells, Tissues, and Organs · Methods in molecular biology (Clifton, N.J.) · 1 Jan 2026

Extracellular ice damage

downin reviews1

1 study
  1. Cryoprotective agents protect against extracellular ice damage.

    Review

    Mass Transfer in Cryopreservation at Multiple Scales: Cells, Tissues, and Organs · Methods in molecular biology (Clifton, N.J.) · 1 Jan 2026

Funding

National Institute of Biomedical Imaging and BioengineeringUS$159.6k1 grant since 2025

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