Computer-aided detection-assisted colonoscopy

Intervention1 paper5 findings

In a human trial of post-polypectomy surveillance, computer-aided detection-assisted colonoscopy increases adenomas detected per procedure and withdrawal time compared with standard colonoscopy, but does not change detection rates for adenomas, advanced adenomas or sessile serrated lesions.

  • Human trial1

Outcomes

5

Colonoscopy withdrawal time

upin humans1Moderate certainty

1 study
  1. Computer-aided detection-assisted colonoscopy increases colonoscopy withdrawal time in humans (16.35±8.32 vs 14.52±7.24 min; p < 0.001).

    Human trialPost-polypectomy surveillance within an organized colorectal cancer screening program; compared with standard colonoscopyn = 914

    Efficacy of artificial intelligence in detecting precancerous lesions among a colorectal cancer screening population undergoing surveillance colonoscopies in Italy: a randomized control trial (GENIAL-CO Follow-Up study) · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 6 Oct 2026

Sessile serrated lesion detection rate

no changein humans1Moderate certainty

1 study
  1. Computer-aided detection-assisted colonoscopy has no effect on sessile serrated lesion detection rate in humans (17.1% vs 14.2%; p = 0.154).

    Human trialPost-polypectomy surveillance within an organized colorectal cancer screening program; compared with standard colonoscopyn = 914

    Efficacy of artificial intelligence in detecting precancerous lesions among a colorectal cancer screening population undergoing surveillance colonoscopies in Italy: a randomized control trial (GENIAL-CO Follow-Up study) · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 6 Oct 2026

Adenomas detected per colonoscopy

upin humans1Moderate certainty

1 study
  1. Computer-aided detection-assisted colonoscopy increases adenomas detected per colonoscopy in humans (1.80±2.19 vs 1.32±1.75; p < 0.001).

    Human trialPost-polypectomy surveillance within an organized colorectal cancer screening program; compared with standard colonoscopyn = 914

    Efficacy of artificial intelligence in detecting precancerous lesions among a colorectal cancer screening population undergoing surveillance colonoscopies in Italy: a randomized control trial (GENIAL-CO Follow-Up study) · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 6 Oct 2026

Advanced adenoma detection rate

no changein humans1Moderate certainty

1 study
  1. Computer-aided detection-assisted colonoscopy has no effect on advanced adenoma detection rate in humans (7.3% vs 6.3%; p = 0.263).

    Human trialPost-polypectomy surveillance within an organized colorectal cancer screening program; compared with standard colonoscopyn = 914

    Efficacy of artificial intelligence in detecting precancerous lesions among a colorectal cancer screening population undergoing surveillance colonoscopies in Italy: a randomized control trial (GENIAL-CO Follow-Up study) · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 6 Oct 2026

Adenoma detection rate

no changein humans1Moderate certainty

1 study
  1. Computer-aided detection-assisted colonoscopy has no effect on adenoma detection rate in humans (66.6% vs 61.0%; p = 0.160).

    Human trialPost-polypectomy surveillance within an organized colorectal cancer screening program; compared with standard colonoscopyn = 914

    Efficacy of artificial intelligence in detecting precancerous lesions among a colorectal cancer screening population undergoing surveillance colonoscopies in Italy: a randomized control trial (GENIAL-CO Follow-Up study) · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 6 Oct 2026

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