Nature Communications
Enzyme reduces a form of protein damage in human tissue
Overnight exposure reduced an age-linked protein modification by 45% in lens proteins from a 64-year-old donor, compared with untreated samples.Overnight exposure reduced an age-linked protein modification by 45% in lens proteins from a 64-year-old donor, compared with untreated samples.
Human cell studyInterventions
Who was studiedHuman lens, skin, and artery samples, against untreated lens protein samples
What changedCMLase-treated human lens proteins had 45% less of an age-linked chemical modification than untreated samples
The catchLens damage reduction differed by assay: 78% by antibody versus 45% by chemical analysis