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CIRCCRIM1 overexpression

CIRCCRIM1 overexpression has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Oct 8, 2022: “CircCRIM1 Ameliorates Endothelial Cell Angiogenesis in Aging through the miR-455-3p/Twist1/VEGFR2 Signaling Axis”.

InterventionPreclinical

1 paper studies it1 findingUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

What did studies of CIRCCRIM1 overexpression find?

1

Studies of CIRCCRIM1 overexpression measured 1 outcome; the most studied are angiogenesis (1 study).

Angiogenesis

upin mice1

1 study

  1. CIRCCRIM1 overexpression improves angiogenesis in mice.

    “Overexpressing circCRIM1 mediated through a plasmid or adeno-associated virus (AAV) reversed the downregulation of angiogenesis-related phenotype acquisition during aging.”

    Animalsin aging mouse model of lower limb ischemia and aging MAECs

    CircCRIM1 Ameliorates Endothelial Cell Angiogenesis in Aging through the miR-455-3p/Twist1/VEGFR2 Signaling Axis

    Oxidative medicine and cellular longevity

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