Cholesterol restriction

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: Australian Research Council and 2 more
  • Model organisms1

Outcomes

2

Intestinal permeability

upin flies1

1 study
  1. Cholesterol restriction increases intestinal permeability in flies.

    “Low-cholesterol diets increased intestinal permeability and reduced lifespan”

    Model organismsintestinefemales

    Short lifespan under dietary cholesterol depletion is associated with gut dysfunction in Drosophila melanogaster females

    npj agingFeb 19, 2026

Lifespan

downin flies1

1 study
  1. Cholesterol restriction shortens lifespan in flies.

    “Low-cholesterol diets increased intestinal permeability and reduced lifespan”

    Model organismsfemales

    Short lifespan under dietary cholesterol depletion is associated with gut dysfunction in Drosophila melanogaster females

    npj agingFeb 19, 2026

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