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Childhood adiposity

Exposure

1 paper studies it2 findings

  • Humans1

Outcomes

2

Intracranial volume

upin silico1

1 study

  1. Childhood adiposity increases intracranial volume in silico (z-score 0.14 (95% CI 0.05, 0.23)).

    “childhood z-score (95% CI) for intracranial volume = 0.14 (0.05, 0.23); P = 0.002”

    In silico

    Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity

    Brain : a journal of neurologyJun 18, 2024

Brain volume

downin silico1

1 study

  1. Childhood adiposity decreases brain volume in silico (z-score difference -0.20 (95% CI -0.28, -0.12)).

    “individuals who were genetically predicted to have had higher levels of adiposity in childhood were found to have multiple smaller adult brain volumes relative to intracranial volume”

    In silico

    Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity

    Brain : a journal of neurologyJun 18, 2024

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