Cascade screening
1 paper2 findings
- 1 lab in 1 country
- Humans1
Outcomes
2Age at diagnosis
downin humans1
1 study
Age at diagnosis
downin humans1
Cascade screening decreases age at diagnosis in humans (~9 years earlier).
Humanscarrier relatives compared with index cases
Research Square12 Aug 2026Preprint
Carrier relative identification
upin humans1
1 study
Carrier relative identification
upin humans1
Cascade screening increases carrier relative identification in humans (68.2% (133/195), 2.6 per index case).
Humansrelatives of genetically confirmed casesn = 195
Research Square12 Aug 2026Preprint
Latest
1 in 12 monthsResearch Square
Cascade screening amplifies familial hypercholesterolaemia detection after clinically guided next- generation sequencing
Preprint: cohort study of 197 peopleInterventions