Capable program

2 papers6 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Human trial1

Outcomes

Nursing home admissions

downin humans1

1 study

Capable program decreases nursing home admissions in humans (7-10x return on investment).
“primarily through reductions in hospitalization and nursing home admissions”
Review
Aging Equity and Institutional Frameworks: The Role of Policy and Applied Interventions
GSA 2025 abstract31 Dec 2025

Hospitalization

downin humans1

1 study

Capable program decreases hospitalization in humans (7-10x return on investment).
“primarily through reductions in hospitalization and nursing home admissions”
Review
Aging Equity and Institutional Frameworks: The Role of Policy and Applied Interventions
GSA 2025 abstract31 Dec 2025

Pain

downin humans1

1 study

Capable program decreases pain in humans (p = 0.01).
“and pain (p = 0.01)”
Human trialn = 30
Implementation of the CAPABLE Program Plus Critical Home Repairs Among Older Veterans
GSA 2025 abstract31 Dec 2025

Depressive symptoms

downin humans1

1 study

Capable program decreases depressive symptoms in humans (p = 0.03).
“depressive symptoms (p = 0.03)”
Human trialn = 30
Implementation of the CAPABLE Program Plus Critical Home Repairs Among Older Veterans
GSA 2025 abstract31 Dec 2025