Cabergoline

Cabergoline decreases T cell exhaustion in mice.

“reducing ductal area and proliferation, and reversing T cell exhaustion”

Animalspost-lactation treatment in K14-Cre; Brca1F/F, Trp53F/F micemammary glandsingle dose

Cabergoline Suppresses Postpartum Breast Cancer by Enhancing Mammary Gland Involution in Brca1-Mutant Mice and Is Associated with Reduced Risk in Younger Women

Cancer discovery·15 Oct 2026

Cabergoline increases mammary gland involution in mice.

“cabergoline treatment remodels the mammary gland by potentiating involution”

Animalspost-lactation treatment in K14-Cre; Brca1F/F, Trp53F/F micemammary glandsingle dose

Cabergoline Suppresses Postpartum Breast Cancer by Enhancing Mammary Gland Involution in Brca1-Mutant Mice and Is Associated with Reduced Risk in Younger Women

Cancer discovery·15 Oct 2026

Cabergoline increases time to postpartum mammary cancer onset in mice.

“delays the onset and reduces the incidence of postpartum mammary cancer in K14-Cre; Brca1F/F, Trp53F/F mice.”

Animalspost-lactation treatment in K14-Cre; Brca1F/F, Trp53F/F micemammary glandsingle dose

Cabergoline Suppresses Postpartum Breast Cancer by Enhancing Mammary Gland Involution in Brca1-Mutant Mice and Is Associated with Reduced Risk in Younger Women

Cancer discovery·15 Oct 2026

Cabergoline decreases postpartum mammary cancer incidence in mice.

“delays the onset and reduces the incidence of postpartum mammary cancer in K14-Cre; Brca1F/F, Trp53F/F mice.”

Animalspost-lactation treatment in K14-Cre; Brca1F/F, Trp53F/F micemammary glandsingle dose

Cabergoline Suppresses Postpartum Breast Cancer by Enhancing Mammary Gland Involution in Brca1-Mutant Mice and Is Associated with Reduced Risk in Younger Women

Cancer discovery·15 Oct 2026

Cabergoline is associated with postpartum breast cancer incidence in humans (approximately 69% lower risk).

“cabergoline treatment was associated with a lower incidence of postpartum breast cancer, with a meta-analysis indicating an approximate 69% reduction in risk.”

Humanstwo independent retrospective cohorts of European women; pooled associationbreastfemales

Cabergoline Suppresses Postpartum Breast Cancer by Enhancing Mammary Gland Involution in Brca1-Mutant Mice and Is Associated with Reduced Risk in Younger Women

Cancer discovery·15 Oct 2026