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(-)bpap

Intervention

2 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Against: findings that point the other way from most findings on the same outcome.

  • 1 lab in 1 country
  • 1 finding against
  • Funders: Emberi Eroforrások Minisztériuma and 2 more
  • Animals2

Outcomes

3

Lifespan

no changein rats1upin rats1

2 studies

  1. (-)bpap has no effect on lifespan in rats.

    “neither could it prolong lifespan.”

    Animalsmales

    Age-related decline of various cognitive functions in well-experienced male rats treated with the putative anti-aging compound (2R)-1-(1-benzofuran-2-yl)-N-propylpentane-2-amine ((-)BPAP)

    GeroScience12 Jun 2023

  2. (-)bpap extends lifespan in rats (P<0.02).

    “Rats treated with 0.0001 or 0.05mg/kg BPAP lived significantly longer than their saline treated peers (P<0.02)”

    Animals0.0001 or 0.05mg/kgmales

    Longevity study with low doses of selegiline/(-)-deprenyl and (2R)-1-(1-benzofuran-2-yl)-N-propylpentane-2-amine (BPAP)

    Life sciences22 Oct 2016

Cognitive function

no changein rats1

1 study

  1. (-)bpap has no effect on cognitive function in rats.

    “BPAP could not improve the cognitive performance; neither could it prolong lifespan.”

    Animalsmales

    Age-related decline of various cognitive functions in well-experienced male rats treated with the putative anti-aging compound (2R)-1-(1-benzofuran-2-yl)-N-propylpentane-2-amine ((-)BPAP)

    GeroScience12 Jun 2023

Learning ability

upin rats1

1 study

  1. (-)bpap improves learning ability in rats.

    “18-month-old rats treated with 0.0001mg/kg BPAP were as good learners as 3-month-old saline treated rats.”

    Animals0.0001mg/kgmales

    Longevity study with low doses of selegiline/(-)-deprenyl and (2R)-1-(1-benzofuran-2-yl)-N-propylpentane-2-amine (BPAP)

    Life sciences22 Oct 2016

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