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Bone marrow mononuclear cell transplantation

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Academia Sinica and 4 more
  • Animals1

Outcomes

2

Cancer resistance

upin mice1

1 study

  1. Bone marrow mononuclear cell transplantation improves cancer resistance in mice.

    “anti-cancer capability, in particular that against melanoma as well as hepatocellular carcinoma, and lifespan-extending property of Klf1(K74R) mice, could be transferred to wild-type mice via transplantation”

    Animalsin wild-type micebone marrow

    Long-term hematopoietic transfer of the anti-cancer and lifespan-extending capabilities of a genetically engineered blood system by transplantation of bone marrow mononuclear cells

    eLife16 May 2024

Lifespan

upin mice1

1 study

  1. Bone marrow mononuclear cell transplantation extends lifespan in mice.

    “lifespan-extending property of Klf1(K74R) mice, could be transferred to wild-type mice via transplantation of their bone marrow mononuclear cells at a young age of the latter.”

    Animalsin wild-type micebone marrow

    Long-term hematopoietic transfer of the anti-cancer and lifespan-extending capabilities of a genetically engineered blood system by transplantation of bone marrow mononuclear cells

    eLife16 May 2024

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