Blood flow restriction resistance training

Studies of blood flow restriction resistance training in people

6 studies gave blood flow restriction resistance training to people and measured what changed

What changedDesignPeopleSource

up: Improves handgrip strength

up: Improves verbal learning and delayed recall

Randomized trial8 weeks36 peopleoldest-oldOlder adults; The oldest old; Coexisting sarcopenia and mild cognitive impairmentBMC geriatrics, Nov 3, 2026

up: Increases SIRT1

Randomized trial16 weeks45 peopleMenType 2 diabetesJournal of diabetes and metabolic disorders, Mar 3, 2026

up: Increases neuromuscular response

Randomized trial17 peopleWomenJournal of strength and conditioning research, Feb 12, 2026

no change: Has no effect on knee extensor strengthmean difference -1.87 Nm (95% CI -10.96 to 7.23)

Randomized trial12 weeks35 people60 years and olderOlder adults; Patient cohortsJournal of clinical medicine, Feb 21, 2019

down: Decreases perceived exertion3.1 ± 0.3 vs 4.8 ± 0.4 (1st set), 5.7 ± 0.4 vs 7.3 ± 0.4 (2nd set), 7.5 ± 0.4 vs 8.6 ± 0.5 (3rd set)

down: Decreases lactate4.5 ± 0.4 mmol vs 6.2 ± 0.7 mmol

no change: Has no effect on systolic blood pressure

Randomized trial18 peopleWomen67.0 ± 1.7 yearsOlder adults; elderly hypertensive women, knee extension exerciseClinical physiology and functional imaging, Jun 10, 2016

up: Increases reactive hyperemia index1.8 ± 0.2 to 2.1 ± 0.3

up: Increases foot transcutaneous oxygen pressure62.4 ± 5.3 to 68.9 ± 5.8 mmHg

down: Decreases von Willebrand factor175.7 ± 20.3 to 156.3 ± 38.1 %

Randomized trial4 weeks20 people71 ± 4 yearsOlder adults; change within the BFR group after 4-week trainingEuropean journal of applied physiology, Jan 28, 2016