JAMA Network Open
Bladder drugs presumed safer not linked to lower dementia risk
Estimated 10-year dementia risk was 20.0% with mirabegron or vibegron, compared with 18.1% with drugs classified as high-risk anticholinergics.Estimated 10-year dementia risk was 20.0% with mirabegron or vibegron, compared with 18.1% with drugs classified as high-risk anticholinergics.
Cohort · 830,393 peopleIncident dementia
Who was studied830,393 adults with overactive bladder, 1046 to 1568 days
What changedEstimated 10-year dementia risk was 20.0% with mirabegron or vibegron versus 18.1% with high-risk anticholinergics
The catchDiagnosis codes or dementia-specific medication can miss unrecognized dementia