Approach bias modification

Approach bias modification has been studied in 2 papers since 2024: 2 trials in people; 1 in the past year. The newest paper, Mar 28, 2026: “The effects of approach bias modification on smoking cue-reactivity in individuals who smoke: A randomized controlled fMRI study”.

Intervention

2 papers study it7 findingsUpdated

See all 2

“with past-week standard drinks significantly decreasing by 18% (p < 0.001)”
Smartphone-delivered approach bias modification for reducing harmful drinking amongst middle-older age adults: Secondary analyses of a single-arm pilot studyDrug and alcohol review2024doi:10.1111/dar.13827

None of its findings points the other way.

  • 2 independent labs in 2 countries
  • Funders: Deutsche Forschungsgemeinschaft and 8 more
  • Human trial2

Studies in people

2 studies gave approach bias modification to people and measured what changed.

What did studies of Approach bias modification find?

5

Studies of Approach bias modification measured 5 outcomes; the most studied are smoking cue-reactivity (1 study), smoking abstinence (1) and alcohol dependence (1).

Smoking cue-reactivity

no changein humans1

1 study
  1. Approach bias modification has no effect on smoking cue-reactivity in humans.

    “Contrary to our hypothesis, omnibus tests revealed no significant group×time interactions on smoking cue-reactivity in any ROI (ps ≥ 0.235; see Table and supplementary results Fig. for boxplot visualization), indicating comparable changes in cue-reactivity across groups.”

    Human trialseven daily sessionsn = 117

    The effects of approach bias modification on smoking cue-reactivity in individuals who smoke: A randomized controlled fMRI study

    Scientific reports

  2. Approach bias modification has no effect on smoking cue-reactivity in humans.

    “Results showed no significant group×time interactions on cue-reactivity”

    Human trialtobacco dependencecomputerized trainingreward-related brain regionsseven sessions45.3% femalesn = 117

    The effects of approach bias modification on smoking cue-reactivity in individuals who smoke: A randomized controlled fMRI study

    Scientific reports

More on Smoking cue-reactivity

Smoking abstinence

no changein humans1

1 study
  1. Approach bias modification has no effect on smoking abstinence in humans (26.2% vs 16.7% vs 23.1%).

    “Regarding group differences in abstinence rates, no significant effects were found at t1 (short-term abstinence; whole sample: 56 of 117 [47.9%], TAU+ApBM: 19 of 42 [45.2%], TAU+Sham: 19 of 36 [52.8%], TAU-only: 18 of 39 [46.2%]; χ2[2] = 0.51, p =.775) and at t2 (long-term abstinence; whole sample: 26 of 117 [22.2%], TAU+ApBM: 11 of 42 [26.2%], TAU+Sham: 6 of 36 [16.7%], TAU-only: 9 of 39 [23.1%]; χ2[2] = 1.04, p =.594”

    Human trialseven daily sessionsn = 117

    The effects of approach bias modification on smoking cue-reactivity in individuals who smoke: A randomized controlled fMRI study

    Scientific reports

  2. Approach bias modification has no effect on smoking abstinence in humans.

    “ApBM did not enhance abstinence rates.”

    Human trialtobacco dependencecomputerized trainingseven sessions45.3% femalesn = 117

    The effects of approach bias modification on smoking cue-reactivity in individuals who smoke: A randomized controlled fMRI study

    Scientific reports

Alcohol dependence

downin humans1

1 study
  1. Approach bias modification decreases alcohol dependence in humans (p < 0.001).

    “significant reductions in drinking days, mean craving and dependence scores (p < 0.001).”

    Human trialsmartphone-delivered and personalized4 weeksn = 289

    Smartphone-delivered approach bias modification for reducing harmful drinking amongst middle-older age adults: Secondary analyses of a single-arm pilot study

    Drug and alcohol review

More on Alcohol dependence

Adherence to alcohol guidelines

upin humans1

1 study
  1. Approach bias modification increases adherence to alcohol guidelines in humans (from 25% to 41% and 6% to 28%, p < 0.001).

    “significant increase in the proportion of drinking within recommended single-session and weekly guidelines post-training (from 25% to 41% and 6% to 28%, respectively, p < 0.001)”

    Human trialsmartphone-delivered and personalized4 weeksn = 289

    Smartphone-delivered approach bias modification for reducing harmful drinking amongst middle-older age adults: Secondary analyses of a single-arm pilot study

    Drug and alcohol review

Alcohol consumption

downin humans1

1 study
  1. Approach bias modification decreases alcohol consumption in humans (-18%, p < 0.001).

    “with past-week standard drinks significantly decreasing by 18% (p < 0.001)”

    Human trialsmartphone-delivered and personalized4 weeksn = 289

    Smartphone-delivered approach bias modification for reducing harmful drinking amongst middle-older age adults: Secondary analyses of a single-arm pilot study

    Drug and alcohol review

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months