Antipsychotic discontinuation

Antipsychotic discontinuation has been studied in 1 paper since 2026: 1 observational study in people; 1 in the past year. The newest paper, May 1, 2026: “Abrupt discontinuation and tapering of antipsychotics in older adults with dementia: a target trial emulation study”.

Exposure

1 paper studies it1 findingUpdated

See all 1 papers on antipsychotic discontinuation

At a glance

The findings reach people, from one lab or study. 1 lab in 2 countries.

“Estimated risks for stroke, pneumonia, and all-cause mortality were similar between strategies.”
Abrupt discontinuation and tapering of antipsychotics in older adults with dementia: a target trial emulation studyThe lancet. Healthy longevity2026doi:10.1016/j.lanhl.2026.100852
Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 2 countries
  • Funders: Monash University and 2 more
  • 1 of 1 finding with company ties
  • Humans1

What did studies of antipsychotic discontinuation find?

1

Studies of antipsychotic discontinuation measured 1 outcome; the most studied are mortality (1 study).

Mortality

no changein humans1

1 study
  1. Antipsychotic discontinuation was not clearly linked with mortality in people living with dementia after 12 weeks of antipsychotic treatment (similar between strategies).

    “Estimated risks for stroke, pneumonia, and all-cause mortality were similar between strategies.”

    Humansin people living with dementia after 12 weeks of antipsychotic treatment24 monthsn = 24,822

    Abrupt discontinuation and tapering of antipsychotics in older adults with dementia: a target trial emulation study

    The lancet. Healthy longevity

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months