Androgen ablation

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

3

Responsiveness to immune checkpoint blockade

upin mice1

1 study
  1. Androgen ablation improves responsiveness to immune checkpoint blockade in mice.

    Animalsimmune checkpoint blockademales

    Lymph node shrinkage limited cancer recognition in male mice

    Nature aging9 Oct 2026

Cancer-specific T cell responses

upin mice1

1 study
  1. Androgen ablation improves cancer-specific T cell responses in mice.

    Animalsmales

    Lymph node shrinkage limited cancer recognition in male mice

    Nature aging9 Oct 2026

Naive CD8+ T cell abundance

upin mice1

1 study
  1. Androgen ablation increases naive CD8+ T cell abundance in mice.

    Animalslymph nodemales

    Lymph node shrinkage limited cancer recognition in male mice

    Nature aging9 Oct 2026

More on Naive CD8+ T cell abundance

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Nature Aging

Lymph node shrinkage limited cancer recognition in male mice

Mouse experiments found earlier loss of immune cells not yet activated by their targets in males, alongside faster lymph node shrinkage.Mouse experiments found earlier loss of immune cells not yet activated by their targets in males, alongside faster lymph node shrinkage.

Experiments in miceCancer