Allogeneic stem cell transplant
Allogeneic stem cell transplant has been studied in 1 paper since 2023: 1 observational study in people. The newest paper, Jul 21, 2023: “Vascular Aging Is Accelerated in Hematological Cancer Survivors Who Undergo Allogeneic Stem Cell Transplant”.
1 paper studies it3 findingsUpdated
“aortic compliance was significantly lower in both SCT groups (overall P=0.007) compared with controls”
1 of its findings points the other way.
- 1 lab in 1 country
- 1 finding against
- 3 of 3 findings with company ties
- Humans1
What did studies of Allogeneic stem cell transplant find?
2Studies of Allogeneic stem cell transplant measured 2 outcomes; the most studied are aortic compliance (1 study) and ventricular-vascular coupling (1).
Aortic compliance
no changein humans1downin humans1
1 study
Aortic compliance
no changein humans1downin humans1
Allogeneic stem cell transplant has no effect on aortic compliance in humans (net difference -0.07 [95% CI, -1.49 to 1.35]).
“In the short-term survivors, no significant group-by-time interactions were observed for any markers of vascular aging from pretransplant to posttransplant”
Humans≈3 months post-SCT
Hypertension (Dallas, Tex. : 1979)
Allogeneic stem cell transplant decreases aortic compliance in humans (P=0.007).
“aortic compliance was significantly lower in both SCT groups (overall P=0.007) compared with controls”
Humanshematologic cancer survivors
Hypertension (Dallas, Tex. : 1979)
Ventricular-vascular coupling
upin humans1
1 study
Ventricular-vascular coupling
upin humans1
Allogeneic stem cell transplant increases ventricular-vascular coupling in humans (P<0.01).
“ventricular-vascular coupling was higher in both survivor groups as was arterial elastance in long-term SCT survivors (ie, worse; P<0.01 for all)”
Humanshematologic cancer survivors
Hypertension (Dallas, Tex. : 1979)