Aggregate rejuvenation
Aggregate rejuvenation has been studied in 1 paper since 2025: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Jun 6, 2025: “Formation of functionally robust human neocartilage from multiple donors using highly expanded costochondral cells”.
1 paper studies it1 findingUpdated
- 1 lab in 1 country
- Funders: California Institute for Regenerative Medicine and 2 more
- Cells1
What did studies of Aggregate rejuvenation find?
1Studies of Aggregate rejuvenation measured 1 outcome; the most studied are ACAN (1 study).
ACAN
upin human cells1
1 study
ACAN
upin human cells1
Aggregate rejuvenation increases ACAN in human cells (>310-fold).
“Aggregate rejuvenation was as effective at P9 as at P5 in restoring a hyaline cartilage-like phenotype, evidenced by increased cell circularity, upregulation of chondrogenic genes”
Cellsat P9 and P5 high passaged cellscostochondral cells
Biofabrication
Latest
Biofabrication
Formation of functionally robust human neocartilage from multiple donors using highly expanded costochondral cells
Experiments in human cellsInterventions