Acupuncture and moxibustion

1. Acupuncture and moxibustion improves knee joint function in humans.

   “Notably, ST36 acupuncture and moxibustion also showed positive effects on sleep quality, knee joint function, and bowel movement patterns”

   Human trial

   A phase 1/2 pilot study of acupuncture and moxibustion at Zusanli (ST36) as a prophylactic treatment in middle-aged and elderly individuals

   Frontiers of medicine·17 Dec 2025

1. Acupuncture and moxibustion decreases α-hydroxybutyrate dehydrogenase in humans (195.50 U/L to 181.00 U/L (P = 0.017)).

   “α-hydroxybutyrate dehydrogenase (α-HBDH) (195.50 U/L (IQR 190.25-212.00) to 181.00 U/L (IQR 165.75-187.25), P = 0.017) at 2 months”

   Human trial2 monthsn = 85

   A phase 1/2 pilot study of acupuncture and moxibustion at Zusanli (ST36) as a prophylactic treatment in middle-aged and elderly individuals

   Frontiers of medicine·17 Dec 2025

More on α-hydroxybutyrate dehydrogenase

1. Acupuncture and moxibustion decreases lactate dehydrogenase in humans (266.50 U/L to 235.50 U/L (P < 0.001)).

   “ST36 intervention led to marked reductions in the levels of lactic dehydrogenase (LDH) (266.50 U/L (IQR 257.50-282.25) to 235.50 U/L (IQR 215.50-244.75), P < 0.001) at 6 months”

   Human trial6 monthsn = 48

   A phase 1/2 pilot study of acupuncture and moxibustion at Zusanli (ST36) as a prophylactic treatment in middle-aged and elderly individuals

   Frontiers of medicine·17 Dec 2025

More on Lactate dehydrogenase

1. Acupuncture and moxibustion decreases uric acid in humans (399.00 μmol/L to 361.00 μmol/L (P = 0.003)).

   “median UA levels decreased from 399.00 μmol/L (IQR 356.00-483.00) to 361.00 μmol/L (IQR 323.00-421.00) (P = 0.003)”

   Human trialin individuals with initially abnormal LDL and UA values6 monthsn = 48

   A phase 1/2 pilot study of acupuncture and moxibustion at Zusanli (ST36) as a prophylactic treatment in middle-aged and elderly individuals

   Frontiers of medicine·17 Dec 2025

More on Uric acid

1. Acupuncture and moxibustion decreases LDL in humans (4.46 mmol/L to 3.97 mmol/L (P = 0.004)).

   “For 6 months acupuncture and moxibustion at ST36 significantly reduced levels of low-density lipoprotein (LDL) and uric acid (UA) in individuals with initially abnormal LDL and UA values.”

   Human trialin individuals with initially abnormal LDL and UA values6 monthsn = 48

   A phase 1/2 pilot study of acupuncture and moxibustion at Zusanli (ST36) as a prophylactic treatment in middle-aged and elderly individuals

   Frontiers of medicine·17 Dec 2025

More on LDL