Activity diversity

3 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

2 independent labs in 1 country
1 finding against

Humans3

Outcomes

Working memory

downin humans1

1 study

Activity diversity decreases working memory in humans.
“on days when individuals engaged in more varied activities than usual, working memory was lower”
Humanswithin-person leveln = 127
Working Memory and Activity Diversity in Older Adults: Examining Within- and Between-Person Associations
GSA 2025 abstract31 Dec 2025

Associations

Working memory

upin humans1

1 study

Activity diversity is associated with working memory in humans.
“at the between-person level, individuals with greater overall activity diversity exhibited better working memory”
Humansbetween-person leveln = 127
Working Memory and Activity Diversity in Older Adults: Examining Within- and Between-Person Associations
GSA 2025 abstract31 Dec 2025

Cognitive function

upin humans1

1 study

Activity diversity is associated with cognitive function in humans.
“Moderation analyses showed that higher activity diversity and frequency were associated with better cognition for both groups”
Humans
HOW CAREGIVING SHAPES THE RELATIONSHIP BETWEEN ACTIVITY DIVERSITY AND COGNITION
GSA 2024 abstract31 Dec 2024