Acanthasteroside B3

Acanthasteroside B3 has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Dec 23, 2022: “Neuritogenic steroid glycosides from crown-of-thorns starfish: Possible involvement of p38 mitogen-activated protein kinase and attenuation of cognitive impairment in senescence-accelerated mice (SAMP8) by peripheral administration”.

Intervention

1 paper studies it2 findingsUpdated

  • 1 lab in 1 country
  • Funders: Government of Japan Ministry of Education Culture Sports Science and Technology and 2 more
  • Animals1

What did studies of Acanthasteroside B3 find?

2

Studies of Acanthasteroside B3 measured 2 outcomes; the most studied are cognitive impairment (1 study) and neurite outgrowth (1).

Cognitive impairment

downin mice1

1 study
  1. Acanthasteroside B3 decreases cognitive impairment in mice.

    “Following subcutaneous administration, acanthasteroside B3 attenuated cognitive impairment of senescence-accelerated mice (SAMP8) in two different cognitive tests.”

    Animalsin SAMP8 mice

    Neuritogenic steroid glycosides from crown-of-thorns starfish: Possible involvement of p38 mitogen-activated protein kinase and attenuation of cognitive impairment in senescence-accelerated mice (SAMP8) by peripheral administration

    Bioorganic & medicinal chemistry

Neurite outgrowth

upin rat cells1

1 study
  1. Acanthasteroside B3 induces neurite outgrowth in rat cells.

    “Acanthasterosides B1 and B3 having two separated xyloses induced neurite outgrowth as like as nerve growth factor (NGF) in the rat pheochromocytoma cell line PC12”

    Cellsin PC12 cellsPC12 cells

    Neuritogenic steroid glycosides from crown-of-thorns starfish: Possible involvement of p38 mitogen-activated protein kinase and attenuation of cognitive impairment in senescence-accelerated mice (SAMP8) by peripheral administration

    Bioorganic & medicinal chemistry

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