AAV-vip
AAV-vip has been studied in 1 paper since 2025: none in people yet, 1 in animals. The research so far is in animals. The newest paper, May 31, 2025: “Overexpression of colonic VIP ameliorates cognitive function and barrier system damage caused by sevoflurane anesthesia and surgery in aged rats with fragile brain functions”.
1 paper studies it3 findingsUpdated
None of its findings points the other way.
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 2 more
- Animals1
What did studies of AAV-vip find?
3Studies of AAV-vip measured 3 outcomes; the most studied are barrier damage (1 study), inflammation (1) and cognitive function (1).
Barrier damage
downin rats1
1 study
Barrier damage
downin rats1
AAV-vip decreases barrier damage in rats.
“promoted the repair of both intestinal mucosal and blood-brain barriers”
Animalsfollowing sevoflurane anesthesia and surgery in rats with fragile brain functioncolon
Experimental neurology
Inflammation
downin rats1
1 study
Inflammation
downin rats1
AAV-vip decreases inflammation in rats.
“attenuated the inflammatory response”
Animalsfollowing sevoflurane anesthesia and surgery in rats with fragile brain functioncolon
Experimental neurology
Cognitive function
upin rats1
1 study
Cognitive function
upin rats1
AAV-vip improves cognitive function in rats.
“VIP upregulation significantly ameliorated post-anesthesia and surgery cognitive deficits”
Animalsfollowing sevoflurane anesthesia and surgery in rats with fragile brain functioncolon
Experimental neurology