5-methyltryptophan

5-methyltryptophan extends lifespan in flies.

“Inhibitors of TDO (alpha-methyl tryptophan) and ABC transporter (5-methyltryptophan) extended life span of wild-type Drosophila.”

Reviewwild-type

Extension of life span by down-regulation of enzymes catalyzing tryptophan conversion into kynurenine: Possible implications for mechanisms of aging

Experimental biology and medicine (Maywood, N.J.)·Jun 10, 2023