POLM

Gene

1 paper2 findings

  • 1 lab in 1 country
  • Animals1

Effects

2

calbindin/alpha-TTP-positive interneurons

downin mice1

1 study
  1. POLM decreases calbindin/alpha-TTP-positive interneurons in mice.

    “A significant decrease of CB/αTTP-positive INs in young Pol μ-/- mice has been detected”

    Animalsin Pol mu-/- micestratum oriens of CA1 region

    Interneurons in the CA1 stratum oriens expressing αTTP may play a role in the delayed-ageing Pol μ mouse model

    Molecular and cellular neurosciencesAug 22, 2024

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Parvalbumin-positive interneurons

downin mice1

1 study
  1. POLM decreases parvalbumin-positive interneurons in mice.

    “although the density of PV-positive INs was lower in the aged Pol μ-/- mice compared to wild-type mice.”

    Animalscompared to wild-type micestratum oriens of CA1 region

    Interneurons in the CA1 stratum oriens expressing αTTP may play a role in the delayed-ageing Pol μ mouse model

    Molecular and cellular neurosciencesAug 22, 2024

More on Parvalbumin-positive interneurons

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