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MEIOK21

Gene

1 paper3 findings

HGNCNCBI GeneTaxon

  • Animals1

Effects

3

Polar body extrusion

upin mouse cells1

1 study

  1. MEIOK21 increases polar body extrusion in mouse cells.

    “Meiok21-/- oocytes also have reduced rates of germinal vesicle breakdown and the first polar body extrusion when cultured in vitro”

    Cellsshown by knockoutfemales

    MEIOK21 regulates oocyte quantity and quality via modulating meiotic recombination

    FASEB journal : official publication of the Federation of American Societies for Experimental BiologyJun 1, 2022

Primordial follicle pool size

upin mice1+40% wild-type

1 study

  1. MEIOK21 increases primordial follicle pool size in mice (~40% of wild-type).

    “the size of the primordial follicle pool in Meiok21-/- females is only ~40% of wild-type females”

    Animalsshown by knockoutfemales

    MEIOK21 regulates oocyte quantity and quality via modulating meiotic recombination

    FASEB journal : official publication of the Federation of American Societies for Experimental BiologyJun 1, 2022

Fertility

upin mice1

1 study

  1. MEIOK21 improves fertility in mice.

    “Meiok21-/- female mice show subfertility.”

    Animalsshown by knockoutfemales

    MEIOK21 regulates oocyte quantity and quality via modulating meiotic recombination

    FASEB journal : official publication of the Federation of American Societies for Experimental BiologyJun 1, 2022

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