LINC01021

1. LINC01021 decreases RBMX in human cells.

   “facilitates DAZAP1-dependent destabilization of RBMX mRNA, leading to activation of the P53 pathway”

   CellsDAZAP1-dependent

   A Primate-Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1-Dependent Destabilization of RBMX

   Aging cell·Jun 25, 2026

More on RBMX

1. LINC01021 impairs motor coordination in mice.

   “ectopic expression of human LINC01021 in mice contributes to aging-like phenotypes, including increased frailty and impaired motor coordination”

   Animalsectopic expression of human LINC01021

   A Primate-Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1-Dependent Destabilization of RBMX

   Aging cell·Jun 25, 2026

1. LINC01021 increases frailty in mice.

   “ectopic expression of human LINC01021 in mice contributes to aging-like phenotypes, including increased frailty and impaired motor coordination”

   Animalsectopic expression of human LINC01021

   A Primate-Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1-Dependent Destabilization of RBMX

   Aging cell·Jun 25, 2026

1. LINC01021 induces cellular senescence in human cells.

   “In human cells, LINC01021 promotes cellular senescence”

   Cells

   A Primate-Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1-Dependent Destabilization of RBMX

   Aging cell·Jun 25, 2026

More on Cellular senescence