ESC Congress 2026 Abstract
Progesterone alleviates blood vessel aging in mice
Mice with their ovaries removed that received daily progesterone for six months showed dose-dependent reversals of blood vessel cell aging, inflammation, and impaired…Mice with their ovaries removed that received daily progesterone for six months showed dose-dependent reversals of blood vessel cell aging, inflammation, and impaired relaxation.
Mouse studyProgesterone
Who was studiedMice with ovaries removed, 6 months, against ovary-removed mice without progesterone
What changedProgesterone reduced blood vessel cell aging in ovary-removed mice compared with no progesterone, with greater reversals at higher doses
The catchSenescence markers and artery relaxation served as proxies for blood vessel aging