EFHD2

Gene1 paper2 findings

Animals1

Effects

2

PHF1 tau

upin mice1

1 study

EFHD2 increases PHF1 tau in mice (medium-to-large main effect).
Animalsin Tau P301L-expressing mice (shown by deletion)cortex
Investigating the role of EFhd2 protein in modulating tau pathology in a tauopathy mouse model · Frontiers in molecular neuroscience · 12 Aug 2026

pSer422 tau

upin mice1

1 study

EFHD2 increases pSer422 tau in mice (medium-to-large main effect).
Animalsin Tau P301L-expressing mice (shown by deletion)cortex
Investigating the role of EFhd2 protein in modulating tau pathology in a tauopathy mouse model · Frontiers in molecular neuroscience · 12 Aug 2026

pSer422 tau →

Latest

1

Frontiers in Molecular NeuroscienceAnimals27 Aug

Investigating the role of EFhd2 protein in modulating tau pathology in a tauopathy mouse model