There is 1 paper on B4GALNT3 in aging research: 1 observational study in people.
At a glance
The findings reach people, from one lab or study. 1 lab in 1 country.
“increasing level of B4GALNT3 gene expression in several tissues was associated with a decreased level of circulating SOST.”
None of its findings points the other way.
Cells and humans: a single group. Worms or flies and mice: nothing yet.
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 1 more
- Humans1
Effects
1Sclerostin protein secretion
downin human cells1
1 study
Sclerostin protein secretion
downin human cells1
B4GALNT3 decreases sclerostin protein secretion in human cells (B4GALNT3 overexpression).
“in vitro evidence validated that B4GALNT3 overexpression significantly decreased SOST protein secretion.”
CellsB4GALNT3 overexpression
Proxied therapeutic inhibition on sclerostin and atrial fibrillation risk
Communications medicine
Associations
1Circulating sclerostin
downin humans1
1 study
Circulating sclerostin
downin humans1
B4GALNT3 is associated with circulating sclerostin in humans.
“increasing level of B4GALNT3 gene expression in several tissues was associated with a decreased level of circulating SOST.”
Humansseveral tissues
Proxied therapeutic inhibition on sclerostin and atrial fibrillation risk
Communications medicine
Latest
1 paper in 12 monthsCommunications Medicine
Proxied therapeutic inhibition on sclerostin and atrial fibrillation risk
Mendelian randomization in peopleMechanisms