Nature Communications
Two cleanup proteins help reset cell lifespan in yeast
A laboratory test designed to assess many samples identified proteins involved in selective cell cleanup as factors in lifespan resetting during reproductive-cell…A laboratory test designed to assess many samples identified proteins involved in selective cell cleanup as factors in lifespan resetting during reproductive-cell formation.
Cell studyMechanisms
Who was studiedBudding yeast gametes, 72 h, against gametes from young double-mutant precursors
What changedGametes lacking both proteins had shorter lifespans when derived from aged rather than young cells
The catchCells nearing senescence could escape the traps, leaving their full lifespans unobserved